BDBM537108 (E)-3-(2-((4-(2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperazin-1-yl)methyl)-1-(((S)-oxetan-2-yl)methyl)-1H-imidazol-5-yl)acrylic acid ::US11897851, Compound 179

SMILES CC1(Oc2cccc(N3CCN(Cc4ncc(\C=C\C(O)=O)n4C[C@@H]4CCO4)CC3)c2O1)c1ccc(Cl)cc1F

InChI Key InChIKey=CROMTTKCTAPBPM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 537108   

TargetGlucagon-like peptide 1 receptor(Human)
Gasherbrum Bio

US Patent
LigandPNGBDBM537108((E)-3-(2-((4-(2-(4-chloro-2-fluorophenyl)-2-methyl...)
Affinity DataEC50:  0.0360nMAssay Description:To optimize functional activity directed toward Gas coupling, a HEK293/CRE-Luc cell line developed by HDB stably expressing the GLP-1 Receptor was us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2024
Entry Details
US Patent