BDBM537841 US11248001, Example 316::US11603523, Example 316

SMILES CSc1cnc(N[C@H]2CC[C@@H](C2)Nc2ccc(cn2)-c2nnc(C)o2)nc1

InChI Key InChIKey=WJYSFZFNIXMGAR-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 537841   

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537841(US11248001, Example 316 | US11603523, Example 316)
Affinity DataKd:  1.10E+3nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CMS (GE Hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetProprotein convertase subtilisin/kexin type 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM537841(US11248001, Example 316 | US11603523, Example 316)
Affinity DataKd:  1.10E+3nMAssay Description:Surface plasmon resonance data was collected on a Biacore T200 or 3000 system (GE Healthcare) at 25° C. Streptavidin was immobilized on a CM5 (GE Hea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent