BDBM538062 4-(3-(1-(3-chloro-5- (trifluoromethyl)pyridin-2- yl)-4-oxido-1,4- azapbosphinan-4-yl)-4- fluorobenzyl)phthalazin- 1(2H)-one::US11248013, Example 20

SMILES O=c1[nH]nc(Cc2ccc(F)c(P3(=O)CCN(c4ncc(C(F)(F)F)cc4Cl)CC3)c2)c2ccccc12

InChI Key InChIKey=XAZWTEGUKFZAAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 538062   

TargetPoly [ADP-ribose] polymerase 1(Human)
Rakovina Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 538062BDBM538062(4-(3-(1-(3-chloro-5- (trifluoromethyl)pyridin-2- y...)
Affinity DataIC50: 550nMAssay Description:Inhibition of PARP-1 enzymatic activities was measured using an HT Universal Colorimetric PARP Assay Kit (Trevigen, catalogue #4677-096-K) following ...More data for this Ligand-Target Pair
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Date in BDB:
6/13/2022
Entry Details
US Patent