BDBM539148 (R)-4-(1-(4-cyclopropylphenyl)-3-(3- methylaminopiperidine-1-carbonyl)-1H- pyrazole-5-yl)benzonitrile::US11254676, Example 2

SMILES CN[C@@H]1CCCN(C1)C(=O)c1cc(-c2ccc(cc2)C#N)n(n1)-c1ccc(cc1)C1CC1

InChI Key InChIKey=OTFMWCLFJQASFK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539148   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539148((R)-4-(1-(4-cyclopropylphenyl)-3-(3- methylaminopi...)
Affinity DataIC50: 29nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent