BDBM539150 (R)-4-(1-(4-cyclopropyl-2-fluorophenyl)- 3-(3-(methylamino)piperidine-1-carbonyl)- 1H-pyrazole-5-yl)benzonitrile::US11254676, Example 4

SMILES CN[C@@H]1CCCN(C1)C(=O)c1cc(-c2ccc(cc2)C#N)n(n1)-c1ccc(cc1F)C1CC1

InChI Key InChIKey=OZOJMZULWADJHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539150   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539150((R)-4-(1-(4-cyclopropyl-2-fluorophenyl)- 3-(3-(met...)
Affinity DataIC50: 38nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
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Date in BDB:
6/19/2022
Entry Details
US Patent