BDBM539166 (R)-4-(1-(4-ethylphenyl)-3-(3-(methyl- amino)piperidine-1-carbonyl)-1H-pyrazole- 5-yl)benzonitrile::US11254676, Example 34

SMILES CCc1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C#N)C(=O)N1CCC[C@H](C1)NC

InChI Key InChIKey=KXRWTQZXJKVRRT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539166   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539166((R)-4-(1-(4-ethylphenyl)-3-(3-(methyl- amino)piper...)
Affinity DataIC50: 47nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent