BDBM539175 (R)-4-(3-(3-aminoazepane-1-carbonyl)- 1-(4-(tert-butyl-2-fluorophenyl)-1H-pyrazole- 5-yl)-2-fluorobenzonitrile::US11254676, Example 44

SMILES CC(C)(C)c1ccc(c(F)c1)-n1nc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CCCC[C@@H](N)C1

InChI Key InChIKey=VZKXHMMNJYRFSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539175   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539175((R)-4-(3-(3-aminoazepane-1-carbonyl)- 1-(4-(tert-b...)
Affinity DataIC50: 23nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
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Date in BDB:
6/19/2022
Entry Details
US Patent