BDBM539191 4-(3-((R)-3-aminopiperidine-1-carbonyl)- 1-(2-fluoro-4-((R)-3-fluoropyrrolidine-1- yl)phenyl)-1H-pyrazole-5-yl)-2-fluorobenzo- nitrile::US11254676, Example 61

SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(-c2ccc(C#N)c(F)c2)n(n1)-c1ccc(cc1F)N1CC[C@@H](F)C1

InChI Key InChIKey=CXCBOBSQBMFELB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539191   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539191(4-(3-((R)-3-aminopiperidine-1-carbonyl)- 1-(2-fluo...)
Affinity DataIC50: 35nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent