BDBM539197 2-fluoro-4-(1-(2-fluoro-4-((S)-3-methoxy- pyrrolidine-1-yl)phenyl)-3-((R)-3-(methyl- amino)piperidine-1-carbonyl)-1H-pyrazole- 5-yl)benzonitrile::US11254676, Example 68

SMILES CN[C@@H]1CCCN(C1)C(=O)c1cc(-c2ccc(C#N)c(F)c2)n(n1)-c1ccc(cc1F)N1CC[C@@H](C1)OC

InChI Key InChIKey=QYKBNQCKAQHEDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539197   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539197(2-fluoro-4-(1-(2-fluoro-4-((S)-3-methoxy- pyrrolid...)
Affinity DataIC50: 22nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
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Date in BDB:
6/19/2022
Entry Details
US Patent