BDBM539198 4-(3-((R)-3-aminopiperidine-1-carbonyl)- 1-(2-fluoro-4-((R)-3-methoxypyrrolidine- 1-yl)phenyl)-1H-pyrazole-5-yl)-2-fluoro- benzonitrile::US11254676, Example 69

SMILES CO[C@@H]1CCN(C1)c1ccc(c(F)c1)-n1nc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1CCC[C@@H](N)C1

InChI Key InChIKey=BQXRMZGIIUTZCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539198   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539198(4-(3-((R)-3-aminopiperidine-1-carbonyl)- 1-(2-fluo...)
Affinity DataIC50: 26nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2022
Entry Details
US Patent