BDBM539216 4-(3-(3-amino-8-azabicyclo[3.2.1]octane- 8-carbonyl)-1-(2-fluoro-4-isopropylphenyl)- 1H-pyrazole-5-yl)-2-fluorobenzonitrile::US11254676, Example 102

SMILES CC(C)c1ccc(c(F)c1)-n1nc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1C2CCC1CC(N)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539216   

TargetLysine-specific histone demethylase 1A(Human)
Hanmi Pharm.

US Patent
LigandPNGBDBM539216(4-(3-(3-amino-8-azabicyclo[3.2.1]octane- 8-carbony...)
Affinity DataIC50: 87nMAssay Description:The biochemical inhibition activity of the synthesized compounds on LSD1 was measured. The activity measurement was performed using LSD1 fluorescence...More data for this Ligand-Target Pair
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Date in BDB:
6/19/2022
Entry Details
US Patent