BDBM540347 (4aR)-N-(2,6-dioxopiperidin- 3-yl)-3-((1-(4-((1R,2S)-6- hydroxy-2-phenyl-1,2,3,4- tetrahydronaphthalen-1-yl)- phenyl)piperidin-4-yl)meth- yl)-1,2,3,4,4a,5-hexahydro- pyrazino[1,2-d]pyrido[2,3-b] [1,4]oxazine-8-carboxamide::US20260028354, Compound A2

SMILES O=C1CCC(NC(=O)c2ccc3c(n2)OC[C@H]2CN(CC4CCN(c5ccc([C@@H]6c7ccc(O)cc7CC[C@@H]6c6ccccc6)cc5)CC4)CCN32)C(=O)N1

InChI Key InChIKey=FPBKPJVBDJHYSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 540347   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
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US Patent
LigandChemical structure of BindingDB Monomer ID 540347BDBM540347((4aR)-N-(2,6-dioxopiperidin- 3-yl)-3-((1-(4-((1R,2...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 540347BDBM540347((4aR)-N-(2,6-dioxopiperidin- 3-yl)-3-((1-(4-((1R,2...)
Affinity DataIC50: 2.75E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent