BDBM540510 (S)-3-((S)-3-(((R)-8-(2-fluoro-4- ((1S,2S)-6-hydroxy-2-phenyl- 1,2,3,4-tetrahydronaphthalen-1- yl)-5-methoxyphenyl)-1-oxa-8- azaspiro[4.5]decan-3-yl)methyl)- 8-oxo-1,2,3,4,4a,5,8,10- octahydro-9H- pyrazino[1',2':4,5][1,4] oxazino[2,3- f]isoindol-9-yl)piperidine-2,6- dione::US20260028354, Compound A173

SMILES COc1cc(N2CCC3(CC2)C[C@H](CN2CCN4c5cc6c(cc5OC[C@@H]4C2)C(=O)N([C@H]2CCC(=O)NC2=O)C6)CO3)c(F)cc1[C@@H]1c2ccc(O)cc2CC[C@@H]1c1ccccc1

InChI Key InChIKey=MMVRZJLBASDUKE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540510   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
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US Patent
LigandChemical structure of BindingDB Monomer ID 540510BDBM540510((S)-3-((S)-3-(((R)-8-(2-fluoro-4- ((1S,2S)-6-hydro...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2026
Entry Details
US Patent