BDBM541387 US11267803, Example 35

SMILES CC(CC1CCCCC1)(NC(=O)c1ccc2ccccc2c1)C(=O)N1C[C@@H](n2nncc2C(C)(C)O)C[C@H]1C(=O)NC1(C(=O)C(N)=O)CCCCC1

InChI Key InChIKey=ZHUWCUMGDLOLJV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 541387   

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541387BDBM541387(US11267803, Example 35)
Affinity DataIC50: 223nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent