BDBM541391 US11267803, Example 39

SMILES CC(C)(O)c1cnnn1[C@H]1C[C@@H](C(=O)NC2(C(=O)C(N)=O)CCCCC2)N(C(=O)C(CC2CC3(CCC3)C2)NC(=O)c2ccc(S(C)(=O)=O)cc2)C1

InChI Key InChIKey=TUYCXDJPOUXQQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 541391   

TargetSerine protease HTRA1(Human)
Orion Ophthalmology

US Patent
LigandChemical structure of BindingDB Monomer ID 541391BDBM541391(US11267803, Example 39)
Affinity DataIC50: 30.5nMAssay Description:Serial dilutions (⅓) from 1000 μM down to 0.051 μM of test compounds were prepared in dimethyl sulfoxide (DMSO). Then 2 μL of so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
US Patent