BDBM542393 US11274090, Example 133 Isomer 2

SMILES Cc1n[nH]c(C)c1-c1ccc(NC(=O)[C@H](NC[C@@H](C)c2ccc(C#N)cc2)c2ccccc2)nc1

InChI Key InChIKey=WWWOMSXOMMVHOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542393   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 542393BDBM542393(US11274090, Example 133 Isomer 2)
Affinity DataIC50: 14.4nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent