BDBM543060 3-(4-{[2- (difluoromethoxy)phenyl]sulfamoyl}phenyl)- 1-(pyridin-3-ylmethyl)urea::US11279687, Compound 69

SMILES FC(F)Oc1ccccc1NS(=O)(=O)c1ccc(NC(=O)NCc2cccnc2)cc1

InChI Key InChIKey=LTENXQQYOGQDOW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543060   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM543060(3-(4-{[2- (difluoromethoxy)phenyl]sulfamoyl}phenyl...)
Affinity DataIC50:  0.600nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent