BDBM543451 US11279699, Compound Example 1

SMILES CS(=O)(=O)C1CN(Cc2ccc(cc2)-c2cccc3nc(NC(=O)C4CC4)nn23)C1

InChI Key InChIKey=ZDGKPRHJLJIZGD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 543451   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543451(US11279699, Compound Example 1)
Affinity DataIC50:  35nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543451(US11279699, Compound Example 1)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543451(US11279699, Compound Example 1)
Affinity DataIC50:  2.43E+3nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543451(US11279699, Compound Example 1)
Affinity DataIC50:  48nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543451(US11279699, Compound Example 1)
Affinity DataIC50:  498nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM543451(US11279699, Compound Example 1)
Affinity DataIC50: >50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent