BDBM543475 (S)-2-((6-chloro-5-(4-(3-hydroxypyrrolidin- 1-yl)phenyl)-1H-imidazo[4,5-b]pyridin-2- yl)thio)acetic acid::US11279702, Compound 7

SMILES O[C@H]1CCN(C1)c1ccc(cc1)-c1nc2nc(SCC(O)=O)[nH]c2cc1Cl

InChI Key InChIKey=QMIKQMBLWSEYOB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 543475   

LigandPNGBDBM543475(US11279702, Compound 7 | (S)-2-((6-chloro-5-(4-(3-...)
Affinity DataEC50:  43nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2022
Entry Details
US Patent