BDBM544052 (M)-6-Chloro- 4-[(2S,5R)-2,5- dimethyl-4- prop-2-enoyl- piperazin-1-yl]- 7-(2,5- dimethyl-3- thienyl)-1-(2- isopropyl-4- methyl-3- pyridyl)pyrido [2,3- d]pyrimidin-2- one::US11285156, Ex.# 92-7
SMILES CC(C)c1nccc(C)c1-n1c2nc(-c3cc(C)sc3C)c(Cl)cc2c(nc1=O)N1C[C@@H](C)N(C[C@@H]1C)C(=O)C=C
InChI Key InChIKey=VHJHIBOMZVGXRQ-MOPGFXCFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 544052
Affinity DataIC50: 31nMAssay Description:Purified GDP-bound KRAS protein (aa 1-169), containing both G12C and C118A amino acid substitutions and an N-terminal His-tag, was pre-incubated in a...More data for this Ligand-Target Pair