BDBM546706 US11292782, Compound 33

SMILES CC1(C)N(C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(CNC(=O)c2ncccn2)cc1

InChI Key InChIKey=GDHSHTOUEIOXKN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 546706   

TargetAndrogen receptor(Human)
Nuvation Bio

US Patent
LigandPNGBDBM546706(US11292782, Compound 33)
Affinity DataIC50: 304nMAssay Description:Human AR cDNA cloned into pCMV vector, GRE-LUC, and CMV-renilla-LUC were used to transfect cells. HEK-293 cells (ATCC) were plated at 120,000 cells p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent