BDBM546888 US11292791, Example 161

SMILES COC(=O)N1[C@H](C)CCc2c1ccc1n([C@@H]3CCC[C@H](CO)C3)c(C[C@@H](C(O)=O)c3ccccc3)nc21

InChI Key InChIKey=ZJMMUZVTMRQJEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 546888   

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM546888(US11292791, Example 161)
Affinity DataIC50: 5.5nMAssay Description:The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM546888(US11292791, Example 161)
Affinity DataIC50: 5.05E+4nMAssay Description:The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent