BDBM547785 (R)-4-((1-Methylcyclobutyl)amino)-2-(3-(pyridin-2-yl)azetidin-1-yl)-6,7-dihydrothieno[3,2-d]pyrimidine 5-oxide::US11292799, Example 15

SMILES CC1(CCC1)Nc1nc(nc2CC[S@@+]([O-])c12)N1CC(C1)c1ccccn1

InChI Key InChIKey=MNQLNCZNAHCANO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547785   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [538-740](Human)
Union Therapeutics

US Patent
LigandPNGBDBM547785((R)-4-((1-Methylcyclobutyl)amino)-2-(3-(pyridin-2-...)
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent