BDBM549034 2-(((2S,4s,6S)-6-((4-(l-methyl-1H-pyrazol-4-yl)benzo[d]thiazol-2-yl)amino)spiro[3.3]heptan-2-yl)oxy)nicotinamide::US11299488, Example 15

SMILES Cn1cc(cn1)-c1cccc2sc(NC3CC4(C3)CC(C4)Oc3ncccc3C(N)=O)nc12

InChI Key InChIKey=FVNBMRSWVSLQHP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549034   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM549034(2-(((2S,4s,6S)-6-((4-(l-methyl-1H-pyrazol-4-yl)ben...)
Affinity DataIC50: 597nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
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Date in BDB:
7/24/2022
Entry Details
US Patent