BDBM549572 US11306075, Ex. 19::US20240158379, Example 19

SMILES COc1cc(ccn1)-c1ccc2oc(CCC(C)=O)c(-c3ccc(Cl)s3)c2c1

InChI Key InChIKey=SOQIMVQSACXUCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549572   

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM549572(US11306075, Ex. 19 | US20240158379, Example 19)
Affinity DataIC50: 2.08E+4nMAssay Description:Tau target (equal mixture of each construct at 300 nM) was prepared in buffer (Tris-HCl pH 7.4) and was incubated in 96-well plates at room temperatu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetMicrotubule-associated protein tau(Human)
Oligomerix

US Patent
LigandPNGBDBM549572(US11306075, Ex. 19 | US20240158379, Example 19)
Affinity DataIC50: 2.08E+4nMAssay Description:AlphaLisa Assay (ALA) was used as a primary screen for identifying compounds that inhibit tau oligomer formation. It is a bead based assay that only ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2024
Entry Details
US Patent