BDBM5496 6-(2-phenylethoxy)-9H-purin-2-amine::CHEMBL446625::O6-Substituted Guanine Deriv. 36

SMILES Nc1nc(OCCc2ccccc2)c2[nH]cnc2n1

InChI Key InChIKey=RSRMQDAEYHBPNN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 5496   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM5496(CHEMBL446625 | 6-(2-phenylethoxy)-9H-purin-2-amine...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Newcastle

LigandPNGBDBM5496(CHEMBL446625 | 6-(2-phenylethoxy)-9H-purin-2-amine...)
Affinity DataIC50: 5.90E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Human)
University of Newcastle

LigandPNGBDBM5496(CHEMBL446625 | 6-(2-phenylethoxy)-9H-purin-2-amine...)
Affinity DataIC50: 6.50E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2005
Entry Details Article
PubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5496(CHEMBL446625 | 6-(2-phenylethoxy)-9H-purin-2-amine...)
Affinity DataIC50: 5.48E+5nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed