BDBM550602 8′-Methyl-6′-({6-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]hept-5-ylcarbonyl]thieno[2,3-d]pyrimidin-4-yl}amino)-2′H-spiro[cyclopentane-1,3′-imidazo[1,5-a]pyridine]-1′,5′-dione::US11311520, Example 96

SMILES Cc1cc(Nc2ncnc3sc(cc23)C(=O)N2C[C@H]3C[C@@H]2CO3)c(=O)n2c1C(=O)NC21CCCC1

InChI Key InChIKey=OFJSXLRXYJZAMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550602   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM550602(8′-Methyl-6′-({6-[(1R,4R)-2-oxa-5-azab...)
Affinity DataIC50: 3.90nMAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent