BDBM550708 (3R,4R) or (3S,4S)-3-(2,3-dihydro-1,4- benzodioxin-6-yl)-2-[4-(1- methylethyl)phenyl]-1-oxo-1,2,3,4- tetrahydroisoquinoline-4-carboxylic acid::US11311528, Ex. 1-3

SMILES CC(C)c1ccc(cc1)N1[C@H]([C@H](C(O)=O)c2ccccc2C1=O)c1ccc2OCCOc2c1

InChI Key InChIKey=MAFNFNOXYXLJAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550708   

LigandPNGBDBM550708((3R,4R) or (3S,4S)-3-(2,3-dihydro-1,4- benzodioxin...)
Affinity DataIC50: 1.16E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent