BDBM550729 (3S,4S) and (3R,4R)-2-(3-cyano-4- morpholin-4-ylphenyl)-3-(2,3-dihydro- 1,4-benzodioxin-6-yl)-1-oxo-1,2,3,4- tetrahydroisoquinoline-4-carboxylic acid::US11311528, Ex. 1-19

SMILES OC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c1ccc(N2CCOCC2)c(c1)C#N)c1ccc2OCCOc2c1

InChI Key InChIKey=UDZAONVFCSWUAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550729   

LigandPNGBDBM550729((3S,4S) and (3R,4R)-2-(3-cyano-4- morpholin-4-ylph...)
Affinity DataIC50: 2.28E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent