BDBM550741 (3S,4S) and (3R,4R)-3-(2,3-dihydro-1,4- benzodioxin-6-yl)-2-[6-(hydroxymethyl)- 5,6,7,8-tetrahydronaphthalen-2-yl]-1- oxo-1,2,3,4-tetrahydroisoquinoline-4- carboxylic acid::US11311528, Ex. 1-31

SMILES OCC1CCc2cc(ccc2C1)N1[C@@H]([C@@H](C(O)=O)c2ccccc2C1=O)c1ccc2OCCOc2c1

InChI Key InChIKey=BELXJXWGJDRLNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550741   

LigandPNGBDBM550741((3S,4S) and (3R,4R)-3-(2,3-dihydro-1,4- benzodioxi...)
Affinity DataIC50: 1.22E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent