BDBM550750 (3S,4S) or (3R,4R)-2-(3,4- dichlorophenyl)-3-(2,3-dihydro-1,4- benzodioxin-6-yl)-1-oxo-1,2,3,4- tetrahydroisoquinoline-4-carboxylic acid::US11311528, Ex. 1-40

SMILES OC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c1ccc(Cl)c(Cl)c1)c1ccc2OCCOc2c1

InChI Key InChIKey=XWALVQJPVULWLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550750   

LigandPNGBDBM550750((3S,4S) or (3R,4R)-2-(3,4- dichlorophenyl)-3-(2,3-...)
Affinity DataIC50: 483nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent