BDBM550756 (3S,4S) and (3R,4R)-3-(2,3-dihydro-1,4- benzodioxin-6-yl)-2-naphthalen-2-yl-1- oxo-1,2,3,4-tetrahydroisoquinoline-4- carboxylic acid::US11311528, Ex. 1-46

SMILES OC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c1ccc2ccccc2c1)c1ccc2OCCOc2c1

InChI Key InChIKey=MLMODOMUGNTNOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550756   

LigandPNGBDBM550756((3S,4S) and (3R,4R)-3-(2,3-dihydro-1,4- benzodioxi...)
Affinity DataIC50: 1.80E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent