BDBM550758 (3S,4S) and (3R,4R)-2-[3-chloro-4-(1- cyano-1-methylethyl)phenyl]-3-(2,3- dihydro-1,4-benzodioxin-6-yl)-1-oxo- 1,2,3,4-tetrahydroisoquinoline-4- carboxylic acid::US11311528, Ex. 1-48

SMILES CC(C)(C#N)c1ccc(cc1Cl)N1[C@@H]([C@@H](C(O)=O)c2ccccc2C1=O)c1ccc2OCCOc2c1

InChI Key InChIKey=UUVRGJZXNYBBIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550758   

LigandPNGBDBM550758((3S,4S) and (3R,4R)-2-[3-chloro-4-(1- cyano-1-meth...)
Affinity DataIC50: 213nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent