BDBM550768 (3R,4R) or (3S,4S)-2-(4-tert-butyl-3- chlorophenyl)-3-(2,3-dihydro-1,4- benzodioxin-6-yl)-6-fluoro-1-oxo- 1,2,3,4-tetrahydroisoquinoline-4- carboxylic acid::US11311528, Ex. 1-58

SMILES CC(C)(C)c1ccc(cc1Cl)N1[C@H]([C@H](C(O)=O)c2cc(F)ccc2C1=O)c1ccc2OCCOc2c1

InChI Key InChIKey=ZRKRCRLPXDWZEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550768   

LigandPNGBDBM550768((3R,4R) or (3S,4S)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 538nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent