BDBM550770 (3R,4R) or (3S,4S)-2-(4-tert-butyl-3- chlorophenyl)-3-(4-methyl-3,4-dihydro- 2H-1,4-benzoxazin-6-yl)-1-oxo-1,2,3,4- tetrahydroisoquinoline-4-carboxylic acid::US11311528, Ex. 1-60::US11311528, Ex. 1-61

SMILES CN1CCOc2ccc(cc12)[C@H]1[C@H](C([O-])=O)c2ccccc2C(=O)N1c1ccc(c(Cl)c1)C(C)(C)C

InChI Key InChIKey=SXVIRVBIRDPDES-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 550770   

LigandPNGBDBM550770((3R,4R) or (3S,4S)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 106nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550770((3R,4R) or (3S,4S)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 7.50E+3nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent