BDBM550774 (3R,4R) or (3S,4S)-2-[3-chloro-4-(1- cyanocyclopropyl)phenyl]-3-(2,3- dihydro-1,4-benzodioxin-6-yl)-1-oxo- 1,2,3,4-tetrahydroisoquinoline-4- carboxylic acid::US11311528, Ex. 1-64

SMILES OC(=O)[C@H]1[C@@H](N(C(=O)c2ccccc12)c1ccc(c(Cl)c1)C1(CC1)C#N)c1ccc2OCCOc2c1

InChI Key InChIKey=XWUORYMGYIYAJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550774   

LigandPNGBDBM550774((3R,4R) or (3S,4S)-2-[3-chloro-4-(1- cyanocyclopro...)
Affinity DataIC50: 225nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent