BDBM550784 (3S,4S) or (3R,4R)-2-(4-tert-butyl-3- chlorophenyl)-3-(2,3-dihydro-1,4- benzodioxin-6-yl)-7-fluoro-1-oxo- 1,2,3,4-tetrahydroisoquinoline-4- carboxamide::US11311528, Ex. 1-74

SMILES CC(C)(C)c1ccc(cc1Cl)N1[C@@H]([C@@H](C(N)=O)c2ccc(F)cc2C1=O)c1ccc2OCCOc2c1

InChI Key InChIKey=VOQHYKWKGMWOQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550784   

LigandPNGBDBM550784((3S,4S) or (3R,4R)-2-(4-tert-butyl-3- chlorophenyl...)
Affinity DataIC50: 209nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent