BDBM550803 8-(1H-indazol-5-yl)-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 10::US11312705, Example 10

SMILES Nc1nc(-c2ccccc2)c(-c2ccc3[nH]ncc3c2)c2nncn12

InChI Key InChIKey=RAJLWMDVQMQVLF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550803   

TargetAdenosine receptor A2a(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550803(8-(1H-indazol-5-yl)-7-phenyl-[1,2,4]triazolo[4,3-c...)
Affinity DataIC50:  0.260nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAdenosine receptor A2b(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550803(8-(1H-indazol-5-yl)-7-phenyl-[1,2,4]triazolo[4,3-c...)
Affinity DataIC50:  91nMAssay Description:CHO-K1/A2bR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 1 mg/ml G418. The cells were digested with the cell separati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetAdenosine receptor A2a(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550803(8-(1H-indazol-5-yl)-7-phenyl-[1,2,4]triazolo[4,3-c...)
Affinity DataIC50:  0.260nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent