BDBM550864 US11312704, Compound 329::US11472793, Compound 329::US11524940, Compound 329

SMILES COc1cccc2[nH]c(cc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(N[C@@H](C)c1ccccc1)C#N

InChI Key

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 550864   

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)
Affinity DataIC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)
Affinity DataIC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)
Affinity DataEC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)
Affinity DataIC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)
Affinity DataIC50: <2.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Pardes Biosciences

US Patent
LigandPNGBDBM550864(US11312704, Compound 329 | US11472793, Compound 32...)
Affinity DataIC50: <2.00E+3nMAssay Description:Compounds are assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent