BDBM551136 3-(7-Chloro-1H-indazol-5-yl)-2-(3-fluorocyclobutyl)-5-::US11312712, Example 250

SMILES FC(F)(F)c1ccc2nc([C@H]3C[C@H](F)C3)n(-c3cc(Cl)c4[nH]ncc4c3)c2n1

InChI Key InChIKey=HCCUWWCHPKCGLK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551136   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 551136BDBM551136(3-(7-Chloro-1H-indazol-5-yl)-2-(3-fluorocyclobutyl...)
Affinity DataIC50: 0.0320nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent