BDBM551218 5-[2-(Difluoromethyl)-6-(trifluoromethyl)pyrrolo[2,3-b]pyridin-1-yl]-7-methyl-::US11312712, Example 336

SMILES Cc1cc(cc2CC(=O)Nc12)-n1c(cc2ccc(nc12)C(F)(F)F)C(F)F

InChI Key InChIKey=NGLZUVCIBKYAEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551218   

TargetVoltage-dependent calcium channel gamma-8 subunit(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM551218(5-[2-(Difluoromethyl)-6-(trifluoromethyl)pyrrolo[2...)
Affinity DataIC50:  0.0100nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent