BDBM551403 2-(1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b: 4,5-c']dipyridine::US11312716, Example 9

SMILES c1cc2[nH]c3nc(-c4cn[nH]c4)ccc3c2cn1

InChI Key InChIKey=NAEQZBNOUXKFFI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551403   

TargetMicrotubule-associated protein tau(Human)
Ucb Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 551403BDBM551403(2-(1H-pyrazol-4-yl)-9H-pyrrolo[2,3-b: 4,5-c']dipyr...)
Affinity DataIC50: 25.1nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent