BDBM551415 2-[6-(morpholin-4-yl)pyridin-3-yl]-9H-pyrrolo[2,3-::US11312716, Example 21

SMILES c1cc2[nH]c3nc(-c4ccc(N5CCOCC5)nc4)ccc3c2cn1

InChI Key InChIKey=BKPKZIXANWRXSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551415   

TargetMicrotubule-associated protein tau(Human)
Ucb Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 551415BDBM551415(2-[6-(morpholin-4-yl)pyridin-3-yl]-9H-pyrrolo[2,3-...)
Affinity DataIC50: 25.1nMAssay Description:[3H]compound binding to Tau protein methods were adapted from Nobuyuki et al (2013). Biological samples as described above (0.2-50 μg proteins p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent