BDBM552046 US11312726, Compound 17

SMILES CC(=O)N1Cc2ccc(NC(=O)C[C@@H]3N=C(c4ccc(Cl)cc4)c4c(sc(C)c4C)-n4c(C)nnc43)cc2C1

InChI Key InChIKey=OTHGJZAORZWPPD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 552046   

TargetBromodomain-containing protein 4 [349-460](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandChemical structure of BindingDB Monomer ID 552046BDBM552046(US11312726, Compound 17)
Affinity DataIC50: 7nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4 [44-167](Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandChemical structure of BindingDB Monomer ID 552046BDBM552046(US11312726, Compound 17)
Affinity DataIC50: 24nMAssay Description:The experiment plate was a plate that contained a gradient concentration of the compound and a corresponding DMSO solution and was prepared with ECHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent