BDBM554448 US11332473, Compound 1.335

SMILES CCn1c(=O)c2cnc(Nc3ccc4c(c3)CCNC4(C)C)nc2n1-c1nc(C(C)(C)C#N)ccc1F

InChI Key InChIKey=MQKLRBJREIZKEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554448   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 554448BDBM554448(US11332473, Compound 1.335)
Affinity DataIC50: 5nMAssay Description:WEE1: IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details
US Patent