BDBM554568 US11339144, Compound I-21::US11339144, Compound I-51

SMILES CN1CC(C1)NC(=O)c1cc2c(Sc3ccc(Cl)cc3Cl)cc(Cl)c(Cl)c2[nH]1

InChI Key InChIKey=RTBHAWCBAVXQEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 554568   

TargetGTP-binding protein Rheb(Human)
Navitor Pharmaceuticals

US Patent
LigandPNGBDBM554568(US11339144, Compound I-21 | US11339144, Compound I...)
Affinity DataIC50: <1.00E+4nMAssay Description:For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGTP-binding protein Rheb(Human)
Navitor Pharmaceuticals

US Patent
LigandPNGBDBM554568(US11339144, Compound I-21 | US11339144, Compound I...)
Affinity DataIC50:  5.50E+5nMAssay Description:For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent