BDBM554926 US11339144, Compound I-395

SMILES OCc1nc2c(OCC3CCCCC3)c(Cl)c(Cl)cc2[nH]1

InChI Key InChIKey=JAPXEWQWNHHRAC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554926   

TargetGTP-binding protein Rheb(Human)
Navitor Pharmaceuticals

US Patent
LigandPNGBDBM554926(US11339144, Compound I-395)
Affinity DataIC50: 1.00E+4nMAssay Description:For the Rheb-dependent in vitro kinase assay, HA-GST-Rheb was first loaded with GTP-γ-S (Millipore #20-176) by incubating 600 ng/μL Rheb wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent