BDBM555250 USRE49080, Example 20

SMILES CC1(C)CNc2cc(Cc3cc(ccc3Cl)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2O1

InChI Key InChIKey=GSTOKDFGXRUKGX-BDHVOXNPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 555250   

TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM555250(USRE49080, Example 20)
Affinity DataIC50: >3.70E+3nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM555250(USRE49080, Example 20)
Affinity DataIC50:  0.550nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent