BDBM556282 US11345701, Compound 7-1
SMILES CC(C)c1nccc(C)c1-n1c2nc(c(F)cc2c(nc1=O)N1C[C@H](C)N([C@H](C)C1)C(=O)C=C)-c1c(F)c(F)c(F)c(N)c1Cl
InChI Key InChIKey=DNXHKKBQRHCFQF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 556282
Affinity DataIC50: 36.7nMAssay Description:NCI-H358 cells expressing KRAS G12C mutant protein were cultured in RPMI 1640 medium (Gibco) containing 10% fetal bovine serum (Gibco). The NCI-H358 ...More data for this Ligand-Target Pair
