BDBM556301 US11345702, Table 1.19::US20230390274, Compound A-8
SMILES FC1(F)CCN(CC1)C(=O)c1ccc2n(cnc2c1)-c1cccc(Cl)c1
InChI Key InChIKey=ONZKJLAEYRQFBC-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 556301
Affinity DataIC50: 12.2nMAssay Description:A hydroxyprostaglandin dehydrogenase inhibition screening biochemical assay can be performed to assess the synthesized inhibitors provided herein. Pr...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The in vitro biochemical assay can be performed in white, 384 plates in total 20 μl reaction volume consisting of 10 nM of 15-PGDH/HPGD (R&D Sys...More data for this Ligand-Target Pair
Affinity DataIC50: 12.2nMAssay Description:The in vitro biochemical assay can be performed in white, 384 plates in total 20 μl reaction volume consisting of 10 nM of 15-PGDH/HPGD (R&D Sys...More data for this Ligand-Target Pair